![]() ![]() Future larger cohort studies are warranted to elucidate the full potential of this promising approach.īurn wound healing and management as a complex and long-lasting process continues to represent a major challenge for patients and health care providers resulting in considerable socio-economic burdens. However, results mainly originate from preclinical and small cohort studies. Conclusions: Acellular fish skin xenografts may represent an effective, low-cost alternative in treatment of superficial- and partial-thickness burns. Existing evidence on the use of acellular fish skin indicates an acceleration of wound healing, reduction in pain and necessary dressing changes as well as treatment-related costs and improved aesthetic and functional outcomes compared to conventional treatment options. Results: In total, 14 trials investigating the effects of acellular fish skin in burn wounds or split-thickness donor sites were determined eligible and included in the present review. Titles and abstracts were screened for the following key terms (variably combined): “fish skin”, “fish skin grafts”, “acellular fish skin”, “Omega3 Wound matrix”, “xenograft”, “burn injury”, “burns”. Materials and Methods: A systematic review of the literature, up to March 2022, was conducted using the electronic databases PubMed and Web of Science. Due to these beneficial wound healing properties, acellular fish skin might represent an effective treatment approach in burn wound management. Acellular fish skin acts as a skin substitute, reducing inflammatory responses and advancing proinflammatory cytokines that promote wound healing. Recent advances in the development of applicable xenografts as an alternative to split-thickness skin grafts have allowed for the development of acellular fish skin. When they were removed after 11 days using petroleum jelly, the wounds look incredible compared to the ones with traditional wrappings.Background and Objectives: Burn wound healing and management continues to be a major challenge for patients and health care providers resulting in a considerable socio-economic burden. The fish skin grafts were also replaced many times to restore the damaged tissue. Tilapia’s skins were left on da Silva’s burn areas for 11 days and longer on her hands, before being removed since the wounds were deeper. ![]() ![]() “But I jumped at the chance because they said it would be far less painful than the normal treatment and easier to manage.” “When doctors suggested putting fish skin on my wounds I found the idea really strange. “I was in absolute agony and desperate for anything to ease my suffering. “The explosion left me with horrific injuries. Maria Ines, 36, who was a waitress in the Casa Velha restaurant in Russas, Brazil at the time of the accident said: She was offered an alternative therapy to the conventional burn cream ones her wounds were to be covered with the skin of a Tilapia fish. In an incident of cooker canister explosion, Maria Ines Candido da Silva suffered from second-degree burns on her arms, neck, and face. The skins can also be stored in refrigerated banks in Sao Paulo in pieces of 10cm by 20cm for up to two years without a hitch. The skin, which is closer to human skin and is flexible is then stretched and laminated around the wound. It is also ensured that any fishy smell is removed before the medical use. The fish skin is put through a rigorous process of removal of scale, muscle tissue, and toxins to eliminate any possibility of disease transfusion. The skin from Tilapia fish was used since it is found to be a disease-resistant species readily found in Brazilian rivers. This pioneering new therapy has significantly reduced the burn trauma and considerably speeds up the healing process.įish scales have been used for the first time as a band-aid to treat lesions, and according to the doctors, they cost half the price of burn medicines. It looks like Tilapia is tipping the scale in the treatments of burn victims! For the first time anywhere in the medical world, Brazilian doctors have started to use the skin of tropical fish Tilapia to treat burn victims. ![]()
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